Comfrey Health Benefits & Medicinal Uses

Comfrey, scientifically known as Symphytum officinale, is a perennial herb native to Europe and parts of Asia. Revered for centuries for its remarkable medicinal properties, it’s also commonly referred to as “knitbone” or “bruisewort” due to its historical use in promoting the healing of bruises, sprains, and fractures.

This herb boasts a robust appearance, with broad, hairy leaves and bell-shaped purple or white flowers. Its roots and leaves are primarily used for medicinal purposes, containing beneficial compounds such as allantoin, rosmarinic acid, and tannins. Allantoin, in particular, contributes significantly to comfrey’s regenerative properties.

The Historical Context

Comfrey holds a rich historical significance, dating back to ancient times. Traditionally, it was utilized for its wound-healing capabilities. The name “comfrey” itself is believed to have derived from the Latin word “confera,” signifying “to grow together,” indicating its historical use in healing bone fractures and wounds.

Ancient Greeks and Romans esteemed comfrey for its healing properties. Additionally, it gained popularity during the Middle Ages as a staple in herbal medicine often used topically in various poultices and salves.

Understanding Its Composition

The composition of comfrey contributes to its healing prowess. The herb contains allantoin, a chemical compound known for promoting cell proliferation and tissue regeneration. This compound aids in wound healing, making it a valuable asset in herbal medicine.

Moreover, comfrey encompasses other constituents like rosmarinic acid and tannins. Rosmarinic acid acts as an anti-inflammatory and antioxidant, while tannins provide astringent properties.

Cultivation and Availability

Cultivating comfrey requires adequate soil and moisture conditions, typically thriving in well-draining soil with partial shade. Its availability is widespread, both in cultivated gardens and in the wild. The plant’s adaptability makes it a sought-after herb for individuals interested in natural remedies.

Why It’s Gained Popularity

In recent times, there has been a resurgence of interest in natural remedies and herbal supplements. Comfrey’s resurgence in popularity is attributed to its historical efficacy in healing wounds and promoting bone health.

Its appeal extends to individuals seeking alternative treatments for various health issues. Its versatility, coupled with its historical significance, has led to increased exploration and research into its potential benefits in modern medicine.

Spiritual and Ceremonial Value

Beyond its medicinal utility, comfrey has held spiritual and ceremonial significance in various cultures throughout history. Its reputation as a healing herb often extended beyond the physical realm, encompassing spiritual and symbolic connotations.

Folklore and Symbolism

Comfrey’s association with healing and regeneration earned it a place in folklore and spiritual practices. In some traditions, it was believed that carrying a piece of comfrey root or wearing it as an amulet could safeguard against harm and promote well-being.

The herb’s ability to accelerate healing was often connected to beliefs in renewal and growth, making it a symbol of resilience and vitality. Its deep roots were also seen as a representation of stability and grounding.

Ritualistic Uses

In certain cultures, comfrey was incorporated into rituals and ceremonies. It was sometimes used in herbal sachets, burned as incense, or infused into teas during healing ceremonies or rites of passage. These practices aimed to harness the herb’s perceived energetic qualities for physical and spiritual well-being.

Healing and Spiritual Connection

The notion of comfrey as a healing plant extended beyond its physical attributes. Many believed that its use fostered a deeper connection with nature and the Earth’s healing energies. This spiritual connection was often emphasized in rituals involving the cultivation or harvesting of comfrey.

Contemporary Perspectives

While the spiritual and ceremonial significance of comfrey persists in some circles, its modern usage primarily focuses on its medicinal applications. However, the historical reverence for comfrey as a healing herb continues to influence its perception and usage among those who seek natural remedies.

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Comfrey Health Benefits

Comfrey has been a subject of interest due to its potential medicinal benefits, owing to its rich composition of beneficial compounds. While its historical use primarily centered around wound healing, modern research has shed light on additional health-promoting properties.

Wound Healing and Tissue Repair

One of the most acclaimed benefits of comfrey is its ability to facilitate wound healing and tissue repair. Allantoin, a key compound in comfrey, aids in cell proliferation, accelerating the healing process. When applied topically, comfrey-based preparations have been historically used to treat cuts, bruises, and minor burns, promoting faster recovery.

Bone Health and Fracture Healing

Comfrey’s historical moniker, “knitbone,” hints at its traditional use in supporting bone health and fracture healing. While historical uses indicate its potential in promoting bone healing, caution is advised due to certain alkaloids present in the plant that might pose risks when taken internally.

Anti-inflammatory and Pain Relief

Rosmarinic acid and other compounds in comfrey exhibit anti-inflammatory properties, potentially offering relief from pain associated with conditions like arthritis and muscle strains. Comfrey-based creams or ointments have been used topically to alleviate pain and reduce inflammation.

Skin Health and Dermatological Conditions

Comfrey’s regenerative properties make it a sought-after ingredient in skincare products. Its application in creams or lotions is believed to aid in skin rejuvenation, potentially benefiting conditions such as eczema and psoriasis.

Respiratory Health

Some traditional practices involve using comfrey preparations to address respiratory issues, although research in this area remains limited. It has been historically used in teas or tinctures for conditions like coughs and bronchitis, although caution is advised due to the presence of potentially harmful alkaloids.

Digestive Health

Comfrey has been historically used in certain traditional medicine systems to address digestive discomfort, although its internal use is discouraged due to safety concerns regarding alkaloid content.

Research and Safety Considerations

While comfrey shows promise in various medicinal applications, it’s crucial to note potential safety concerns. Certain alkaloids present in comfrey, notably pyrrolizidine alkaloids, are known to be hepatotoxic and may cause liver damage if ingested in large amounts or over an extended period.

comfrey benefits

Herbs That Can Be Combined With Comfrey

In herbal medicine, the synergy between different herbs can enhance their benefits, creating powerful combinations. Comfrey, with its healing properties, blends harmoniously with several other herbs, amplifying their respective effects.


Arnica, known for its anti-inflammatory properties, pairs well with comfrey in topical formulations. Together, they create potent creams or ointments that aid in reducing inflammation, relieving pain, and accelerating the healing of bruises and muscle soreness.


Calendula recognized for its skin-soothing and healing properties, complements comfrey in skincare preparations. Their combination in creams or salves can promote skin rejuvenation, benefiting conditions such as eczema, minor burns, and cuts.


Chamomile, renowned for its calming and anti-inflammatory effects, pairs synergistically with Comfrey. When combined, they create soothing preparations that alleviate skin irritation, enhance wound healing, and offer relief from minor skin conditions.

St. John’s Wort

St. John’s Wort, known for its potential antidepressant and anti-inflammatory properties, can complement comfrey in certain topical applications. Their combination may aid in reducing nerve pain, muscle discomfort, and mild skin irritations.


Echinacea, prized for its immune-boosting properties, when combined with comfrey, might offer added support in healing minor wounds or skin irritations. The combination could potentially enhance the body’s natural healing mechanisms.


Sage, with its antimicrobial and anti-inflammatory properties, can be combined with Comfrey in topical applications. Together, they may assist in soothing skin conditions, promoting wound healing, and reducing inflammation.

Precautions When Combining Herbs

While combining herbs can offer various benefits, it’s crucial to exercise caution. Some individuals might be sensitive or allergic to specific herbs, leading to adverse reactions. Before using any herbal combination, especially if you have underlying health conditions or are on medication, consult a healthcare professional or herbalist.

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Warnings, Side Effects & Medicinal Interaction

While comfrey exhibits promising medicinal properties, it’s essential to be aware of potential side effects and precautions associated with its usage, particularly due to the presence of pyrrolizidine alkaloids.

Liver Toxicity

Pyrrolizidine alkaloids found in comfrey have been linked to liver toxicity. Prolonged or excessive consumption of comfrey, especially in the form of teas or supplements, may pose a risk of liver damage. As a precautionary measure, internal use of comfrey is discouraged due to this potential hazard.

Skin Sensitivity

Some individuals may experience skin sensitivity or allergic reactions when applying comfrey topically. Patch testing before widespread application is advisable, especially for those with sensitive skin or known plant allergies.

Pregnancy and Breastfeeding

Due to the potential risks associated with pyrrolizidine alkaloids, pregnant and breastfeeding individuals are advised to avoid using comfrey internally or externally to prevent any potential harm to the fetus or nursing infant.

Drug Interactions

Comfrey might interact with certain medications, affecting their efficacy or causing adverse reactions. Individuals taking medications metabolized by the liver, such as statins, should exercise caution when considering the use of comfrey due to its potential impact on liver function.

Long-Term Use

Long-term or excessive use of comfrey, even externally, can potentially lead to the accumulation of alkaloids in the body, increasing the risk of adverse effects. Using comfrey for extended periods should be avoided to mitigate potential health risks.

Consultation and Professional Advice

It’s crucial to seek guidance from a qualified healthcare professional, herbalist, or naturopath before incorporating comfrey into your healthcare regimen, especially if you have existing health conditions or are taking medications.

Regulatory Restrictions

In some regions, regulatory authorities have imposed restrictions or warnings regarding the sale or use of comfrey due to its potential toxicity. Understanding and adhering to local regulations is essential when considering the use of comfrey-based products.

Understanding the appropriate dosage forms and recommended dosages for Comfrey is crucial to ensure safe usage and maximize potential benefits while minimizing risks.

Topical Applications

Topical application is the primary and safest method of using comfrey. Comfrey-based creams, ointments, or poultices are widely available and can be applied directly to the affected area. Follow the manufacturer’s instructions or consult a healthcare professional for appropriate usage guidelines.

Precautions for Topical Use

When applying comfrey topically, it’s essential to avoid using it on open wounds or broken skin to prevent potential systemic absorption of pyrrolizidine alkaloids. Additionally, discontinue use if any adverse reactions like skin irritation or redness occur.

Avoiding Internal Use

Due to safety concerns regarding pyrrolizidine alkaloids and their potential liver toxicity, internal consumption of comfrey, whether in the form of teas, capsules, or tinctures, is strongly discouraged.

Professional Guidance

Consulting a qualified healthcare professional, herbalist, or naturopath is recommended before using comfrey, especially if you have underlying health conditions, are taking medications, or are pregnant or breastfeeding.

Safe Usage Duration

Using comfrey topically for short durations as recommended on product labels or by healthcare professionals is advisable. Prolonged or frequent applications should be avoided to minimize potential risks.

Purchasing Considerations

When purchasing comfrey-based products, ensure they are obtained from reputable sources that adhere to quality standards. Look for products with clear labeling and avoid those that promote internal use or lack proper usage instructions.

Regulatory Compliance

Adhering to regulatory guidelines and restrictions regarding the sale and use of comfrey-based products is crucial. Stay informed about local regulations and warnings issued by health authorities.

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Final Thoughts

Comfrey, with its rich historical significance and acclaimed healing properties, remains a compelling herb in the realm of herbal medicine. Its association with wound healing, tissue repair, and potential benefits for skin conditions has captured the interest of herbalists and health enthusiasts alike.

Key Takeaways:

  • Historical Significance: Comfrey holds a deep-rooted historical legacy as a healing herb, valued for wound healing and tissue repair throughout centuries.
  • Composition and Benefits: The herb’s composition, including allantoin and rosmarinic acid, contributes to its therapeutic properties, particularly in wound healing and skin conditions.
  • Safety Considerations: Caution is crucial due to pyrrolizidine alkaloids potentially causing liver toxicity. Topical application, professional guidance, and adherence to dosage recommendations are essential.
  • Synergy in Herbal Combinations: Comfrey harmonizes well with various herbs, creating potent blends that enhance their healing capabilities when used responsibly.
  • Consultation and Precautions: Seeking guidance from healthcare professionals or herbalists before incorporating comfrey is vital, especially for individuals with health conditions or on medications.
  • Embracing Herbal Wisdom: While modern medicine advances, the wisdom of traditional herbal remedies remains significant, offering alternative paths to health and wellness.

Comfrey’s allure in herbal medicine persists due to its historical significance and potential benefits. However, navigating its usage requires a balanced approach that prioritizes safety, informed decision-making, and professional guidance. Embracing the synergy between traditional herbal wisdom and modern knowledge is pivotal for holistic well-being.

Frequently Asked Questions

Comfrey: Answering 50 Questions to Unlock the Secrets of Nature’s Healing Herb

Article Sources

At AncientHerbsWisdom, our content relies on reputable sources, including peer-reviewed studies, to substantiate the information presented in our articles. Our primary objective is to ensure our content is thoroughly fact-checked, maintaining a commitment to accuracy, reliability, and trustworthiness.

  1. National Library of Medicine, National Institutes of Health. Comfrey.
  2. Drugs and Lactation Database, National Library of Medicine. Comfrey.
  3. NIH Office of Dietary Supplements. Dietary Supplements: What you need to know.
  4. National Library of Medicine, National Institutes of Health. LiverTox: clinical and research information on drug-induced liver injury.
  5. Kucera A, Barna M, Holcova S, Horacek O, Hladiková M, Ottillinger B. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. Int J Pediatr Adolesc Med. 2018;5(4):135-141. doi:10.1016/j.ijpam.2018.11.002
  6. Medline Plus, National Library of Medicine. Drug-induced liver injury.
  7. Vickers AJ, Vertosick EA, Lewith G, et al. Acupuncture for chronic pain: Update of an individual patient data meta-analysis. J Pain. 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005
  8. Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. Herbal medicine for low back pain: A Cochrane review. Spine (Phila Pa 1976). 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe
  9. Adeneye AA. Subchronic and chronic toxicities of african medicinal plants. In: Toxicological Survey of African Medicinal Plants. Elsevier; 2014:99-133. doi:10.1016/B978-0-12-800018-2.00006-6
  10. Staiger, C. Comfrey root: from tradition to modern clinical trials. Wien Med Wochenschr. 2013;163:58–64. doi:10.1007/s10354-012-0162-4
  11. Mei N, Chen T, Ning B, Guo L. Transcriptomic profiling for safety and toxicity evaluation of nutraceuticals. In: Nutraceuticals. Elsevier; 2021:299-313. doi:10.1016/B978-0-12-821038-3.00022-7
  12. Frost R, MacPherson H, O’Meara S. A critical scoping review of external uses of comfrey (Symphytum spp.). Complement Ther Med. 2013;21(6):724-745. doi:10.1016/j.ctim.2013.09.009
  13. Staiger, C. (2012, October). Comfrey: A clinical overview. Phytotherapy Research, 28(10), 1441-1448
  14. Staiger, C. (2013). Comfrey root: From tradition to modern clinical trials. Wiener Medizinische Wochenschrift (1946), 163(3), 58-64. 
  15. Staiger C. (2012). Comfrey: a clinical overview. Phytotherapy research : PTR, 26(10), 1441–1448. 
  16. Drug record: Comfrey (Symphytum officinale). (2016, June 28)
  17. Dubey A. Possibility and scope of transdermal comfrey multipurpose nano patch: for the treatment of broken bones, wounds and external ulcers. Pharm Pharmacol Int J. 2017;5(1):4. doi:10.15406/ppij.2017.05.00106
  18. Pabst H, Schaefer A, Staiger C, Junker-Samek M, Predel HG. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Phytother Res. 2013;27(6):811-817. doi:10.1002/ptr.4790
  19. Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. Cochrane Database Syst Rev. 2013;5(5):CD010538. doi:10.1002/14651858.CD010538
  20. Salehi B, Sharopov F, Boyunegmez Tumer T, et al. Symphytum species: a comprehensive review on chemical composition, food applications and phytopharmacology. Molecules. 2019;24(12):2272. doi:10.3390/molecules24122272
  21. Navarro VJ, Khan I, Björnsson E, Seeff LB, Serrano J, Hoofnagle JH. Liver injury from herbal and dietary supplements. Hepatology. 2017;65(1):363-373. doi:10.1002/hep.28813
  22. National Center for Complementary and Integrative Health. Complementary health approaches for chronic pain: what the science says.
  23. Avila C, Breakspear I, Hawrelak J, Salmond S, Evans S. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Fitoterapia. 2020;142:104519. doi:10.1016/j.fitote.2020.104519
  24. Frost, R., MacPherson, H., & O’Meara, S. (2013, December). A critical scoping review of external uses of comfrey (Symphytum spp.). Complementary Therapies in Medicine, 21(6), 724-745
  25. Pabst, H., Schaefer, A., Staiger, C., Junker-Samek, M., & Predel, H. G. (2013, June). Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or lower back pain: A multicentre randomised controlled trial. Phytotherapy Research, 27(6), 811-817
  27. Moreira R, Pereira DM, Valentão P, Andrade PB. Pyrrolizidine Alkaloids: Chemistry, pharmacology, toxicology and food safety. Int J Mol Sci. 2018;19(6):1668. doi:10.3390/ijms19061668