Discovering Gotu Kola: Your Comprehensive Guide with 50 Answers

In the world of herbal remedies and natural wellness, some plants stand out for their myriad benefits. Gotu Kola, an herb with a long history of traditional use, is one such botanical treasure. Its potential to support cognitive function, skin health, and overall well-being has sparked curiosity and interest among those seeking natural alternatives to enhance their lives. In this comprehensive guide, we delve into the many facets of Gotu Kola, providing you with 50 answers to your most pressing questions about this remarkable herb.

Gotu Kola: 50 Questions & Answers

What is Gotu Kola?

Gotu Kola, also known as Centella asiatica, is a small, herbaceous plant native to parts of Asia, particularly India, Sri Lanka, and Southeast Asia. It’s renowned for its various medicinal and therapeutic properties, and it has a long history of use in traditional Ayurvedic and Chinese medicine.

What is the scientific name of Gotu Kola?

The scientific name of Gotu Kola is Centella asiatica. This botanical name is widely recognized and used in the scientific community.

Does Gotu Kola have other common names?

Yes, Gotu Kola goes by several common names depending on the region. In addition to Centella asiatica, it may be referred to as Asiatic Pennywort, Indian Pennywort, Mandukaparni (in Sanskrit), or Bai Bua Bok (in Thai), among others.

What is Gotu Kola’s traditional and modern medicinal use?

Traditionally, Gotu Kola has been used for a variety of health purposes. In Ayurvedic medicine, it’s believed to enhance cognitive function, improve memory, and support wound healing. In Chinese medicine, it has been used to promote longevity and as a remedy for various ailments.

In modern times, Gotu Kola has gained popularity as a herbal remedy with potential cognitive benefits. Some studies suggest it may improve cognitive function, reduce anxiety, and aid in the management of venous insufficiency. Additionally, it’s used topically in skincare products for its potential to promote wound healing and improve skin health.

What nutrients (vitamins, minerals, antioxidants, etc.) does Gotu Kola contain?

Gotu Kola contains a range of nutrients and bioactive compounds. It is a source of vitamins such as vitamin C and vitamin A, as well as essential minerals like calcium, potassium, and magnesium. Additionally, Gotu Kola contains a group of triterpenoids called asiaticosides, which are believed to contribute to its medicinal properties. These compounds have antioxidant and anti-inflammatory effects, which may play a role in Gotu Kola’s potential health benefits.

Find the Best Gotu Kola Products

Thousands of customer reviews are available to help you make the right choice. Embrace the power of nature!

Are there any potential side effects associated with Gotu Kola?

Gotu Kola is generally considered safe when used as directed, but like any herbal supplement, it can have potential side effects in some individuals. Common side effects may include mild digestive issues such as stomach upset or nausea. Additionally, some people might experience skin allergies or rashes when applying Gotu Kola topically. However, these side effects are relatively rare.

The recommended dosage of Gotu Kola can vary depending on the form of the supplement and the intended use. For dried herb capsules or tablets, a typical dosage ranges from 300 to 600 milligrams, taken two to three times a day. When using a tincture, a standard dose is about 30 to 60 drops, diluted in water, up to three times daily. However, it’s essential to consult with a healthcare professional or follow the product label’s instructions for precise dosing as individual needs may vary.

Is Gotu Kola safe for pregnant or breastfeeding women?

Pregnant and breastfeeding women should exercise caution when considering the use of Gotu Kola. While it has a long history of traditional use for various purposes, there is limited scientific research on its safety during pregnancy and breastfeeding. It is advisable to consult with a healthcare provider before using Gotu Kola in any form during these periods to ensure the safety of both the mother and the baby.

Can children safely consume Gotu Kola?

Gotu Kola is generally not recommended for children without guidance from a healthcare professional. There is limited research on its safety and efficacy in pediatric populations, and the dosing for children may differ significantly from that of adults. It is crucial to seek expert advice before giving Gotu Kola to children to ensure appropriate dosing and safety.

How should Gotu Kola be prepared or consumed (e.g., tea, tincture, capsules, tablets)?

Gotu Kola can be consumed in various forms, depending on personal preference and intended use. It is commonly available as dried herb capsules or tablets, which can be taken with water. Some people also make Gotu Kola tea by steeping dried leaves in hot water. Additionally, Gotu Kola tinctures are available, which can be diluted in water or juice before consumption. The choice of preparation method primarily depends on the convenience and desired therapeutic effect, but it’s important to follow recommended dosages and consult with a healthcare professional for guidance on the best approach for your specific needs.

Are there any contraindications or health conditions that may be worsened by Gotu Kola?

Gotu Kola is generally considered safe for most people when used as directed. However, it’s essential to be aware of potential contraindications and interactions. Individuals with liver disease should exercise caution, as some studies suggest that high doses of Gotu Kola may have hepatotoxic effects. Additionally, if you’re pregnant or breastfeeding, it’s advisable to consult your healthcare provider before using Gotu Kola, as its safety during these periods is not well-established. Always discuss any concerns with a healthcare professional to ensure it aligns with your specific health conditions.

Where is Gotu Kola usually sourced or cultivated?

Gotu Kola, scientifically known as Centella asiatica, is primarily sourced and cultivated in tropical and subtropical regions of Asia, including India, Sri Lanka, Indonesia, and Malaysia. It thrives in wet and marshy areas, where it has been used for centuries in traditional medicine and culinary practices.

Yes, Gotu Kola is legal to possess and use in the United States. It is considered a dietary supplement and is readily available in various forms, such as capsules, extracts, and teas, in health food stores and online. However, it’s crucial to purchase products from reputable sources to ensure quality and safety.

Are there any known allergens in Gotu Kola?

Gotu Kola itself is not a common allergen, and allergic reactions to it are rare. However, as with any substance, individual sensitivities can vary. If you have a history of allergies or sensitivities to plants in the Apiaceae family (such as parsley, celery, or carrots), you should exercise caution when trying Gotu Kola for the first time. It’s advisable to start with a small dose and monitor for any adverse reactions.

May Gotu Kola supplements contain contaminants like pesticides or heavy metals?

Contaminants like pesticides and heavy metals can be a concern in herbal supplements, including Gotu Kola. To mitigate this risk, it’s crucial to purchase products from reputable manufacturers who adhere to strict quality control standards. Look for brands that provide third-party testing certificates, which ensure that the product is free from harmful contaminants. Additionally, buying organic Gotu Kola may reduce the likelihood of pesticide residues, as organic farming practices typically limit the use of synthetic pesticides. Always read product labels and do your research to make informed choices when selecting Gotu Kola supplements.

Are there any known long-term effects of using Gotu Kola?

Gotu Kola is generally considered safe for short-term use when taken at recommended doses. However, there’s limited research on its long-term effects. Some studies have suggested that long-term use may be safe, but more comprehensive research is needed. It’s essential to consult with a healthcare professional before using Gotu Kola for an extended period, especially if you have pre-existing medical conditions or are taking other medications.

Do Gotu Kola supplements have a specific shelf life or expiration date?

Yes, like all supplements, Gotu Kola supplements have a shelf life and an expiration date. The shelf life can vary between different brands and forms of supplements. Typically, the expiration date is printed on the packaging. It’s crucial to check this date before use, as expired supplements may not provide the desired effects and could potentially be harmful.

What is the best time of day to take Gotu Kola?

The best time to take Gotu Kola can vary from person to person, as it may depend on individual preferences and how it affects you. Some people find it more energizing and prefer taking it in the morning to help with focus and alertness, while others might take it in the evening to promote relaxation and sleep. It’s advisable to start with a lower dose and experiment with different times to determine what works best for you.

Should Gotu Kola pills be taken with food or on an empty stomach?

Gotu Kola supplements can be taken with or without food, depending on your preference and how your body reacts to it. Taking it with food may help reduce the risk of stomach upset for some individuals. However, others prefer taking it on an empty stomach for potentially quicker absorption. It’s recommended to follow the instructions on the product label or consult with a healthcare provider for personalized guidance.

Are there any dietary restrictions or guidelines while using Gotu Kola?

While using Gotu Kola, there are no specific dietary restrictions, but it’s essential to maintain a balanced and healthy diet for overall well-being. It’s advisable to avoid excessive caffeine or alcohol consumption, as these substances may interact with Gotu Kola. Additionally, if you are on medication or have underlying health conditions, consult with a healthcare professional to ensure there are no potential interactions or contraindications with your diet. Always use Gotu Kola supplements as directed and in moderation.

The recommended duration of use for Gotu Kola can vary depending on individual needs and health goals. In general, it is safe for short-term use (a few weeks to a few months) to address specific health concerns. However, for long-term use, it’s advisable to consult with a healthcare professional to determine the appropriate duration, as prolonged use may not be suitable for everyone.

Is it advisable to consult a healthcare professional before using Gotu Kola?

Yes, it is advisable to consult a healthcare professional before using Gotu Kola, especially if you have underlying medical conditions, are taking medications, or are pregnant or nursing. Consulting a healthcare provider can help ensure that Gotu Kola is safe and appropriate for your specific health situation.

Are there any special precautions for storing Gotu Kola supplements?

When it comes to storing Gotu Kola supplements, it’s important to keep them in a cool, dry place, away from direct sunlight and moisture. A sealed container or the original packaging is recommended to maintain freshness and potency. Following these precautions will help ensure the quality of the supplements over time.

How does Gotu Kola taste, and can it be mixed with other herbs or foods for palatability?

Gotu Kola has a mildly bitter taste, which some people find tolerable, while others may not enjoy it on its own. To improve palatability, you can mix Gotu Kola with other herbs or foods. Many people prefer blending it into smoothies, adding it to herbal teas, or mixing it with honey to mask the bitterness.

What other supplements work well together with Gotu Kola?

Gotu Kola, a renowned adaptogenic herb, can be effectively combined with various other supplements and herbs to support different aspects of health and well-being. Here are some complementary supplements and herbs that work well with Gotu Kola:

  • Ginkgo Biloba: The combination of Gotu Kola and Ginkgo Biloba can enhance cognitive function, memory, and overall brain health. They both have neuroprotective properties and may support mental clarity.
  • Ashwagandha: Gotu Kola and Ashwagandha are adaptogens that work together to combat stress and anxiety. They can help promote a sense of calm and emotional well-being.
  • Bacopa Monnieri: Combining Gotu Kola with Bacopa Monnieri can further support memory and cognitive function. This combination is often used to enhance learning and focus.
  • Turmeric (Curcumin): Gotu Kola and curcumin, the active compound in Turmeric, can work in harmony to reduce inflammation and support joint health. This combination may be beneficial for those dealing with arthritis or joint discomfort.
  • L-Theanine: Gotu Kola and L-Theanine, commonly found in green tea, can provide a calming effect without drowsiness. This combination is ideal for promoting relaxation and reducing anxiety.
  • Rhodiola Rosea: Combining Gotu Kola with Rhodiola Rosea can enhance your body’s ability to adapt to stress. This duo may provide a more profound sense of balance and energy.
  • Lemon Balm: Gotu Kola and Lemon Balm can be combined for relaxation and stress relief. This blend is often used to ease anxiety and promote a sense of calm.
  • Milk Thistle: The combination of Gotu Kola and Milk Thistle can support liver health and detoxification. It’s a good choice for those looking to promote overall well-being.

Is there any scientific research or clinical evidence supporting Gotu Kola’s effectiveness?

Yes, there is a growing body of scientific research and clinical evidence that supports the effectiveness of Gotu Kola (Centella asiatica) for various health benefits. Studies have shown its potential to improve cognitive function, promote wound healing, reduce anxiety, and alleviate symptoms of venous insufficiency. However, it’s important to note that while promising, more research is needed to fully understand its mechanisms and potential applications.

Find the Best Gotu Kola Products

Thousands of customer reviews are available to help you make the right choice. Embrace the power of nature!

Are there any age restrictions for using Gotu Kola (e.g., suitable for the elderly)?

Gotu Kola is generally considered safe for people of all ages when used in recommended doses. It has a long history of traditional use, including among the elderly, for its potential cognitive and circulatory benefits. However, as with any herbal supplement, it’s advisable to consult with a healthcare professional before starting Gotu Kola, especially if you have underlying medical conditions or are taking other medications.

Does Gotu Kola require a specific preparation method, such as decoction or infusion?

Gotu Kola can be prepared in various ways, including as a tea (infusion) or as a tincture. Making Gotu Kola tea involves steeping dried or fresh leaves in hot water for several minutes. Some traditional preparations also involve decoction, where the leaves are simmered in water to extract their active compounds. Additionally, Gotu Kola extracts and capsules are available for those who prefer a more convenient option. The choice of preparation method depends on individual preference and intended use.

Can Gotu Kola be used topically (externally) in addition to internal consumption?

Yes, Gotu Kola can be used topically as well as internally. It is commonly incorporated into skincare products due to its potential for promoting wound healing, reducing inflammation, and improving skin elasticity. Topical creams, ointments, and serums containing Gotu Kola extract are available and can be applied to the skin as directed for various dermatological benefits.

Are there any known symptoms of overdose or excessive use of Gotu Kola?

While Gotu Kola is generally safe when used appropriately, excessive consumption may lead to side effects such as stomach upset, headache, and dizziness. However, cases of overdose are rare, and the symptoms are usually mild. It’s essential to follow the recommended dosage guidelines provided on the product label or as advised by a healthcare professional to avoid any potential adverse effects. If you experience any unusual or severe symptoms after using Gotu Kola, it’s advisable to seek medical attention promptly.

What is Gotu Kola’s mode of action within the body?

Gotu Kola’s mode of action within the body involves its active compounds, namely triterpenoid saponins, and asiaticoside. These compounds are believed to support collagen production, improve blood circulation, and exhibit anti-inflammatory properties. As a result, Gotu Kola is often associated with wound healing, skin health, and cognitive function enhancement.

Are there any known synergistic effects when Gotu Kola is combined with specific nutrients?

Yes, there are known synergistic effects when Gotu Kola is combined with specific nutrients. For instance, when paired with vitamin C, it may enhance collagen synthesis due to its role in collagen formation. Additionally, combining Gotu Kola with adaptogenic herbs like Ashwagandha may offer stress-reduction benefits.

Does Gotu Kola have a distinct aroma or essential oil that may have therapeutic benefits?

Gotu Kola does have a distinct aroma and essential oil, although it is not as potent as other aromatic herbs. The essential oil extracted from Gotu Kola may possess mild therapeutic benefits, such as calming effects when used in aromatherapy or massage.

Are there any cultural or historical uses of Gotu Kola that should be considered?

Gotu Kola boasts a rich history of cultural and historical uses. It has been used in traditional Ayurvedic and Chinese medicine for centuries to promote wound healing, improve cognitive function, and enhance overall vitality. In Sri Lanka, it is also known as “Brahmi” and is considered a brain tonic.

Does Gotu Kola have any spiritual or ceremonial significance in certain traditions?

Yes, Gotu Kola holds spiritual and ceremonial significance in certain traditions. In Ayurveda, it is considered one of the “sattvic” herbs, promoting clarity of mind and spiritual growth. Some Buddhist monks have traditionally consumed Gotu Kola to aid meditation and enhance mental focus, as it is believed to balance the mind and body. This spiritual connection underscores its value beyond its physical health benefits.

Are there any variations in Gotu Kola’s potency based on its geographic origin?

Yes, there can be variations in Gotu Kola’s potency depending on its geographic origin. The chemical composition of Gotu Kola, scientifically known as Centella asiatica, can vary based on the environmental conditions, soil quality, and climate in which it is grown. In some regions, Gotu Kola may have higher concentrations of active compounds like asiaticoside and madecassoside, making it potentially more potent.

Does Gotu Kola have a known effect on specific organs or body systems?

Gotu Kola is known to have effects on several organs and body systems. It is renowned for its potential benefits on the skin, as it may promote collagen production and wound healing. Additionally, Gotu Kola has been studied for its positive impact on the circulatory system, potentially improving venous insufficiency and circulation. Some research also suggests its influence on the nervous system, potentially enhancing cognitive function and reducing anxiety.

Are there any known interactions of Gotu Kola with commonly prescribed medications?

Gotu Kola may interact with certain commonly prescribed medications. It has mild blood-thinning properties, which means it may interact with anticoagulant medications like warfarin or antiplatelet drugs like aspirin. Therefore, it’s crucial to consult with a healthcare provider if you are taking such medications to avoid potential complications.

What are the potential benefits and risks of long-term or chronic use of Gotu Kola?

When considering long-term or chronic use of Gotu Kola, it’s essential to weigh the potential benefits against the risks. Some individuals may experience mild side effects like digestive disturbances or skin allergies. While there is limited evidence of long-term risks, it’s advisable to use Gotu Kola under the guidance of a healthcare professional and to periodically assess its ongoing suitability for your needs.

Is it advisable to cycle on and off Gotu Kola to prevent tolerance or dependence?

Whether to cycle on and off Gotu Kola to prevent tolerance or dependence depends on individual circumstances. Unlike substances that commonly lead to dependence, Gotu Kola is not considered addictive. However, some users choose to cycle it to maintain its effectiveness, as prolonged use may lead to reduced responsiveness in some cases. It’s a personal choice, and consulting with a healthcare provider can help determine the most suitable approach for your specific needs.

Are there any precautions regarding driving or operating machinery while using Gotu Kola?

When using Gotu Kola, it’s essential to be cautious about activities requiring alertness, such as driving or operating machinery. Gotu Kola may cause drowsiness or mild sedation in some individuals, primarily when taken in higher doses or in combination with other sedating substances. If you experience drowsiness, it’s advisable to refrain from such activities until you’re sure of how Gotu Kola affects you. Always start with a low dose and gradually increase it to gauge your response.

Generally, there are no strict dietary restrictions associated with Gotu Kola use. However, it’s wise to maintain a balanced and healthy diet to maximize the herb’s benefits. Some people prefer to avoid caffeine or other stimulants while using Gotu Kola to minimize potential interactions that could increase nervousness or restlessness.

Additionally, maintaining a stress-free lifestyle can complement the herb’s soothing effects. Incorporating relaxation techniques like meditation, yoga, or deep breathing exercises may enhance the overall benefits of Gotu Kola.

Does Gotu Kola have any specific recommendations for addressing common side effects?

Common side effects of Gotu Kola are generally mild and include gastrointestinal discomfort or skin irritation in rare cases. To address these, it’s advisable to take Gotu Kola with food to minimize stomach upset. If you experience skin irritation, discontinuing use and consulting a healthcare professional is recommended.

Are there any known variations or subspecies of Gotu Kola with different properties?

Centella asiatica, commonly known as Gotu Kola, is the primary species used for its medicinal properties. While there are related species in the Centella genus, they may not have the same therapeutic benefits. It’s crucial to source and use Centella asiatica for its well-documented medicinal properties, as other species may not offer the same effects.

Does Gotu Kola have any documented cases of misuse or abuse?

Gotu Kola is generally considered safe when used as directed and in appropriate doses. There are no documented cases of misuse or abuse associated with Gotu Kola. However, like any herbal supplement, it’s essential to use it responsibly and follow recommended dosages to avoid potential adverse effects. If you have concerns or questions about using Gotu Kola, consult a healthcare professional for personalized guidance.

Is Gotu Kola regulated or approved for medicinal use in the United States?

Gotu Kola is considered a dietary supplement in the United States, and it is not regulated as a medication by the FDA (Food and Drug Administration). Therefore, it doesn’t require approval for medicinal use. However, it’s important to note that the FDA monitors the safety and labeling of dietary supplements. The quality and purity of Gotu Kola supplements can vary among manufacturers, so it’s advisable to choose products from reputable companies that follow good manufacturing practices.

Are there any known interactions of Gotu Kola when combined with other medicinal herbs?

Gotu Kola may interact with certain medicinal herbs and medications. It’s essential to exercise caution when combining it with anticoagulants (blood-thinning drugs) or herbs like ginkgo biloba, garlic, or ginger, as it could potentially increase the risk of bleeding. Additionally, interactions with drugs for high blood pressure or diabetes may occur, so it’s advisable to consult with a healthcare provider before combining Gotu Kola with other herbs or medications to ensure safety and efficacy.

How does Gotu Kola’s preparation or dosage change for acute versus chronic conditions?

The preparation and dosage of Gotu Kola can vary depending on the specific condition and individual needs. For acute conditions, such as wound healing or minor inflammation, topical preparations like creams or ointments containing Gotu Kola extract may be applied as needed. For chronic conditions, including anxiety or cognitive support, oral supplements in capsule or tincture form are typically recommended. The appropriate dosage can vary widely, but a common guideline is to start with a low dose and gradually increase it while monitoring for any adverse effects. Consulting with a healthcare provider or herbalist for personalized guidance is advisable.

Find the Best Gotu Kola Products

Thousands of customer reviews are available to help you make the right choice. Embrace the power of nature!

Are there any known withdrawal symptoms when discontinuing the use of Gotu Kola?

There are no well-documented withdrawal symptoms associated with discontinuing the use of Gotu Kola. However, like with any herbal supplement, individual responses may vary. It’s generally recommended to taper off the use of Gotu Kola gradually if you’ve been taking it regularly for an extended period. This approach can help minimize any potential rebound effects or discomfort that might occur when ceasing its use abruptly.

What are the best supplement brands of Gotu Kola?

Choosing a reputable supplement brand is essential to ensure product quality and safety. Some well-known and trusted brands that offer Gotu Kola supplements include Nature’s Way, Gaia Herbs, and Solaray. However, it’s crucial to read product labels, check for third-party testing, and consider your specific needs when selecting a brand. Additionally, consulting with a healthcare provider or herbalist can provide personalized recommendations based on your health goals and concerns.

Article References & Sources

At AncientHerbsWisdom, our content relies on reputable sources, including peer-reviewed studies, to substantiate the information presented in our articles. Our primary objective is to ensure our content is thoroughly fact-checked, maintaining a commitment to accuracy, reliability, and trustworthiness.

  1. MedlinePlus. A guide to herbal remedies.
  2. Ganie IB, Ahmad Z, Shahzad A, et al. Biotechnological Intervention and Secondary Metabolite Production in Centella asiatica L. Plants (Basel). 2022;11(21):2928. Published 2022 Oct 30. doi:10.3390/plants11212928
  3. Farhana, K. M., et al. (2016). Effectiveness of gotu kola extract 750 mg and 1000 mg compared with folic acid 3 mg in improving vascular cognitive impairment after stroke.
  4. Matsuda H, Morikawa T, Ueda H, Yoshikawa M. Medicinal foodstuffs. XXVII. Saponin constituents of gotu kola (2): structures of new ursane- and oleanane-type triterpene oligoglycosides, centellasaponins B, C, and D, from Centella asiatica cultivated in Sri Lanka. Chem Pharm Bull (Tokyo). 2001;49(10):1368-1371. doi:10.1248/cpb.49.1368
  5. Gotu kola. (2019).
  6. Wattanathorn J, Mator L, Muchimapura S, et al. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. Journal of Ethnopharmacology. 2008;116(2):325-332. doi: 10.1016/j.jep.2007.11.038
  7. Gray, N. E., et al. (2018). Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification.
  8. Puttarak P, Dilothornsakui P, Saokaew S, et al. Effects of Centella asiatica (L.) urb. on cognitive function and mood-related outcomes: A systematic review and meta-analysis. Sci Rep. 2017;7(1):10646. doi:10.1038/s41598-017-09823-9
  9. Sabaragamuwa, R., et al. (2018). Centella asiatica (Gotu kola) as a neuroprotectant and its potential role in healthy aging [Abstract].
  10. Martinez-Zapata MJ, Vernooij RWM, Simancas-Racines D, et al. Phlebotonics for venous insufficiency. Cochrane Database of Systematic Reviews. 2020;11:CD003229. doi: 10.1002/14651858.CD003229.pub4
  11. Prakash, A., & Kumar, A. (2013). Mitoprotective effect of Centella asiatica against aluminum-induced neurotoxicity in rats: Possible relevance to its anti-oxidant and anti-apoptosis mechanism [Abstract].
  12. Saeidinia A, Keihanian F, Lashkari AP, et al. Partial-thickness burn wounds healing by topical treatment. Medicine (Baltimore). 2017;96(9): e6168. doi: 10.1097%2FMD.0000000000006168
  13. National Institutes of Health Office of Dietary Supplements. Dietary supplement label database.
  14. Thanthong A, Nanthong R, Kongwattanakul S, et al. Prophylaxis of radiation-induced dermatitis in patients with breast cancer using herbal creams: a prospective randomized controlled trial. Integrative Cancer Therapies. 2020;19:1534735420920714. doi: 10.1177%2F1534735420920714
  15. Gotu kola. (n.d.).
  16. Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Dańczak-Pazdrowska A, Brzezińska M. Centella asiatica in dermatology: an overview. Phytother Res. 2014;28(8):1117-1124. doi:10.1002/ptr.5110
  17. Cesarone, M. R., et al. (2001). Effects of the total triterpenic fraction of Centella asiatica in venous hypertensive microangiopathy: A prospective, placebo-controlled, randomized trial [Abstract].
  18. Haslan H, Suhaimi FH, Das S. Herbal Supplements and Hepatotoxicity: A Short Review. Nat Prod Commun. 2015;10(10):1779-1784.
  19. Gohil, K. J., et al. (2010). Pharmacological review on Centella asiatica: A potential herbal cure-all.
  20. National Institute of Diabetes and Digestive and Kidney Diseases. LiverTox: Acute liver failure.
  21. Cesarone, M. R., et al. (2001). Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: A clinical prospective randomized trial with a microcirculatory model [Abstract].
  22. Kusumastuti SA, Nugrahaningsih DAA, Wahyuningsih MSH. Centella asiatica (L.) extract attenuates inflammation and improve insulin sensitivity in a coculture of lipopolysaccharide (LPS)-induced 3T3-L1 adipocytes and RAW 264.7 macrophages. Drug Discov Ther. 2019;13(5):261-267. doi:10.5582/ddt.2019.01052
  23. Kumari S, Deori M, Elancheran R, Kotoky J, Devi R. In vitro and In vivo Antioxidant, Anti-hyperlipidemic Properties and Chemical Characterization of Centella asiatica (L.) Extract. Front Pharmacol. 2016;7:400. Published 2016 Oct 28. doi:10.3389/fphar.2016.00400
  24. Puttarak, P., et al. (2017). Effects of Centella asiatica (L.) Urb. on cognitive function and mood-related outcomes: A systematic review and meta-analysis.

Valuable Resources