Rhodiola Rosea Benefits: Your Comprehensive Q&A Guide

In this comprehensive Q&A guide, we delve into the wide-ranging benefits of Rhodiola Rosea, addressing common queries and providing insights into its potential for enhancing your overall health and well-being. Whether you’re curious about its uses, potential side effects, or strategies for its incorporation into your daily regimen, we’ve got you covered. Let’s explore the world of Rhodiola Rosea and how it can positively influence your life.

Rhodiola Rosea: 50 Questions & Answers

What is Rhodiola Rosea?

Rhodiola Rosea is a flowering plant known for its medicinal properties. It’s often used as an adaptogen, which means it may help the body adapt to stress and various environmental factors. In traditional medicine, particularly in Russia and Scandinavia, Rhodiola Rosea has been used for centuries to combat fatigue, enhance endurance, and improve overall resilience.

What is the scientific name of Rhodiola Rosea?

The scientific name of Rhodiola Rosea is, unsurprisingly, “Rhodiola Rosea.” It’s sometimes referred to as the “golden root” due to its yellowish-gold roots.

Does Rhodiola Rosea have other common names?

Rhodiola Rosea has several common names, including “Arctic root,” “Roseroot,” “Golden root,” and “Aaron’s rod.”

What is Rhodiola Rosea’s traditional and modern medicinal use?

Rhodiola Rosea has a rich history of medicinal use. Traditionally, it was employed to alleviate fatigue, boost physical and mental endurance, and enhance resilience to harsh climates. In modern times, it’s gaining popularity as a natural remedy for managing stress, improving cognitive function, and combating symptoms of anxiety and depression. Some studies suggest it may also enhance athletic performance and support weight management.

What nutrients (vitamins, minerals, antioxidants, etc.) does Rhodiola Rosea contain?

Rhodiola Rosea contains various nutrients and bioactive compounds. It’s rich in polyphenols, including flavonoids and proanthocyanidins, which possess antioxidant properties. It also contains a range of essential vitamins and minerals, such as vitamin C, vitamin B1 (thiamine), vitamin B2 (riboflavin), zinc, iron, and magnesium. These components contribute to its adaptogenic and health-promoting effects, helping the body cope with stress and maintain overall well-being.

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Are there any potential side effects associated with Rhodiola Rosea?

Rhodiola Rosea is generally considered safe when taken within recommended dosages. However, like many supplements, it may have some potential side effects. Common side effects include mild dizziness, dry mouth, or excessive salivation. These effects are usually mild and temporary. Some individuals may also experience insomnia or restlessness if they take Rhodiola Rosea too late in the day. It’s essential to start with a lower dose to gauge your body’s reaction and increase it gradually if needed.

The recommended dosage of Rhodiola Rosea can vary depending on factors like the product’s potency and your specific health needs. However, a typical starting dose is around 200-300 milligrams per day of a standardized extract containing 3% rosavins and 1% salidroside. For maximum effectiveness, it’s advisable to take it in the morning on an empty stomach to minimize the risk of sleep disturbances. It’s crucial to follow the product-specific dosage recommendations provided on the supplement label or consult with a healthcare professional for personalized guidance.

Is Rhodiola Rosea safe for pregnant or breastfeeding women?

While Rhodiola Rosea is generally considered safe for most people, pregnant and breastfeeding women should exercise caution. There is limited research on its safety in these specific populations, so it’s best to consult with a healthcare provider before using Rhodiola Rosea during pregnancy or while nursing to ensure it won’t have any adverse effects on you or your baby.

Can children safely consume Rhodiola Rosea?

Rhodiola Rosea is primarily intended for adult use, and its safety and efficacy in children have not been extensively studied. It’s advisable to avoid giving Rhodiola Rosea to children unless specifically recommended and supervised by a healthcare professional.

How should Rhodiola Rosea be prepared or consumed (e.g., tea, tincture, capsules, tablets)?

Rhodiola Rosea is commonly available in various forms, including capsules, tablets, tinctures, and teas. The choice of preparation depends on personal preference and convenience. Capsules and tablets offer precise dosing and are easy to incorporate into your daily routine. Tinctures provide a concentrated liquid form, which can be mixed with water or juice. Rhodiola Rosea tea is made by steeping the dried root in hot water, and it offers a traditional way to consume the herb. The choice between these forms ultimately depends on your preference and how you find it most convenient to incorporate into your daily routine. It’s essential to follow the recommended dosage instructions provided on the product packaging or by a healthcare professional.

Are there any contraindications or health conditions that may be worsened by Rhodiola Rosea?

Rhodiola Rosea is generally considered safe when used as directed. However, it’s essential to be aware of potential contraindications and interactions. Individuals with bipolar disorder, for instance, should exercise caution, as Rhodiola may exacerbate manic symptoms. People with certain medical conditions, such as heart disorders or hypertension, should consult their healthcare provider before using Rhodiola, as it may affect blood pressure. Additionally, those taking antidepressants or stimulant medications should discuss potential interactions with their doctor.

Where is Rhodiola Rosea usually sourced or cultivated?

Rhodiola Rosea is native to high-altitude regions in Europe, Asia, and North America. It thrives in cold and mountainous areas, often found in countries like Russia, China, and Scandinavia. Commercially, Rhodiola is cultivated in various regions worldwide, including the United States, Canada, and some European countries. It’s crucial to ensure that the Rhodiola source is reputable, as the quality of the herb can vary depending on the region and cultivation practices.

Rhodiola Rosea is generally considered safe and does not contain common allergens like gluten, dairy, or nuts. However, individuals with known allergies to plants in the Crassulaceae family, to which Rhodiola belongs, should exercise caution. Allergic reactions to Rhodiola are rare but possible, so it’s advisable to start with a small dose and monitor for any adverse effects.

Are there any known allergens in Rhodiola Rosea?

The quality of Rhodiola supplements can vary depending on the manufacturer. To mitigate the risk of contaminants like pesticides or heavy metals, it’s essential to choose products from reputable brands that conduct rigorous testing and adhere to quality control standards. Look for supplements that are third-party tested and certified for purity and potency, as this ensures a higher level of safety and product quality.

May Rhodiola Rosea supplements contain contaminants like pesticides or heavy metals?

Rhodiola Rosea supplements, like any other herbal products, can potentially contain contaminants such as pesticides or heavy metals if they are not properly sourced and manufactured. To minimize this risk, it’s essential to choose reputable brands and products that adhere to good manufacturing practices (GMP). These manufacturers often conduct rigorous testing on their products to ensure they meet safety standards and are free from harmful contaminants. Reading product labels and reviews can also help you select a trustworthy option.

Are there any known long-term effects of using Rhodiola Rosea?

Rhodiola Rosea is generally considered safe when used at recommended doses. However, there is limited research on the long-term effects of Rhodiola Rosea supplementation, as most studies have focused on short-term use. It’s essential to follow the dosing instructions provided on the product label and consult with a healthcare professional before using it for an extended period. Some individuals may experience side effects like sleep disturbances or digestive issues, which should be monitored.

Do Rhodiola Rosea supplements have a specific shelf life or expiration date?

Rhodiola Rosea supplements typically come with a specific shelf life or expiration date, which is mentioned on the product packaging. It’s crucial to adhere to this date, as the potency and effectiveness of the supplement may decrease over time. Using Rhodiola Rosea supplements beyond their expiration date is not recommended, as they may not provide the desired benefits.

What is the best time of day to take Rhodiola Rosea?

The best time to take Rhodiola Rosea can vary from person to person, as its effects can differ based on individual preferences and goals. Some people find that taking it in the morning helps boost energy and focus throughout the day. Others may prefer taking it in the afternoon to combat afternoon fatigue. It’s advisable to start with a low dose and monitor how your body responds to determine the best time for you. Additionally, consider avoiding Rhodiola Rosea close to bedtime, as it may interfere with sleep for some individuals.

Should Rhodiola Rosea pills be taken with food or on an empty stomach?

Rhodiola Rosea supplements can generally be taken with or without food, depending on personal preference. Taking them with food may help reduce the likelihood of gastrointestinal discomfort for some individuals. However, taking them on an empty stomach may lead to quicker absorption and potentially faster effects. Experimenting with both methods and observing how your body responds can help you determine the most suitable way to take Rhodiola Rosea for your specific needs.

Are there any dietary restrictions or guidelines while using Rhodiola Rosea?

While there are no strict dietary restrictions associated with Rhodiola Rosea, it’s advisable to take it with a meal or snack to minimize the risk of potential gastrointestinal discomfort. Some users find it helpful to avoid consuming caffeine or alcohol within a few hours of taking Rhodiola Rosea to maximize its effects.

The recommended duration of use for Rhodiola Rosea can vary depending on individual needs and goals. Generally, it is safe for short-term use (a few weeks to a few months) to address specific stress-related issues or improve physical and mental performance. However, long-term use should be discussed with a healthcare professional.

Is it advisable to consult a healthcare professional before using Rhodiola Rosea?

Consulting a healthcare professional before using Rhodiola Rosea is a prudent step, especially if you have underlying health conditions, are pregnant or nursing, or are taking medications. They can provide personalized guidance and monitor potential interactions or side effects.

Are there any special precautions for storing Rhodiola Rosea supplements?

To maintain the potency of Rhodiola Rosea supplements, it’s essential to store them in a cool, dry place away from direct sunlight and moisture. Keeping them in their original airtight container or a dark glass jar can help protect them from degradation. Ensure the lid is tightly closed to prevent air exposure.

How does Rhodiola Rosea taste, and can it be mixed with other herbs or foods for palatability?

Rhodiola Rosea has a slightly bitter and earthy taste, which some people find tolerable. If you’re not fond of the taste, you can mix it with other herbs, beverages, or foods to make it more palatable. Popular choices include blending it into smoothies, adding it to tea, or mixing it with honey. Experiment with different combinations to find what suits your taste buds best.

What other supplements work well together with Rhodiola Rosea?

Rhodiola Rosea pairs well with several other supplements to create a holistic approach to health and well-being. Here are some supplements that complement Rhodiola Rosea effectively:

  • Ashwagandha: Rhodiola Rosea and Ashwagandha are both adaptogens known for their stress-reducing properties. Combining them can provide comprehensive support for managing stress and anxiety.
  • Ginkgo Biloba: If you’re looking to enhance cognitive function and memory, combining Rhodiola Rosea with Ginkgo Biloba is an excellent choice. This combination supports mental clarity and focus.
  • Panax Ginseng: Both Rhodiola Rosea and Panax Ginseng are adaptogenic herbs that improve energy and vitality. Combining them can increase stamina and reduce fatigue, making it an excellent choice for improving physical performance.
  • L-Theanine: For a calm and focused mind without drowsiness, consider combining Rhodiola Rosea with L-Theanine, a compound found in green tea. This pairing is ideal for stress reduction and relaxation.
  • Turmeric (Curcumin): Combining Rhodiola Rosea with Turmeric, specifically curcumin, can help reduce inflammation and promote joint health. This combination is beneficial for pain relief and improved mobility.
  • Maca Root: Rhodiola Rosea and Maca Root work well together to boost energy and stamina. Athletes often use this combination to enhance physical performance.
  • Holy Basil (Tulsi): Rhodiola Rosea and Holy Basil are both adaptogens that support stress management and overall resilience. Combining them can improve your ability to cope with stressors.
  • Milk Thistle: If you’re looking to support liver health, consider combining Rhodiola Rosea with Milk Thistle. This combination can help detoxify the liver and support its optimal function.
  • Omega-3 Fatty Acids: Combining Rhodiola Rosea with Omega-3 fatty acids, typically sourced from fish oil, can support cardiovascular health and reduce inflammation.

Is there any scientific research or clinical evidence supporting Rhodiola Rosea’s effectiveness?

Yes, there is a growing body of scientific research and clinical evidence supporting the effectiveness of Rhodiola Rosea. Studies suggest that it can help reduce stress, improve mood, enhance cognitive function, and boost physical endurance. Its adaptogenic properties have been studied for their potential to manage the body’s response to stress and promote overall well-being. While more research is needed to fully understand its mechanisms and benefits, the existing evidence is promising.

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Are there any age restrictions for using Rhodiola Rosea (e.g., suitable for the elderly)?

Rhodiola Rosea is generally considered safe for adults of all ages, including the elderly. Its adaptogenic properties may be particularly beneficial for older individuals, helping them cope with stress and maintain cognitive function. However, it’s essential for seniors to consult with a healthcare provider before adding any new supplement to their regimen, as individual health conditions and medications can influence its suitability.

Does Rhodiola Rosea require a specific preparation method, such as decoction or infusion?

Rhodiola Rosea is typically consumed in the form of standardized extracts, capsules, or tablets. These formulations ensure consistent dosages of active compounds like rosavins and salidroside, which are responsible for its therapeutic effects. While some traditional preparations involve decoctions or infusions using the root, standardized supplements are more convenient and reliable for achieving desired health benefits.

Can Rhodiola Rosea be used topically (externally) in addition to internal consumption?

Rhodiola Rosea is primarily used for internal consumption, as it exerts its adaptogenic and stress-reducing effects when ingested. There is limited evidence regarding its topical application, and it’s not commonly used in this manner. It’s important to follow recommended dosage guidelines for internal use and consult with a healthcare professional if considering alternative applications.

Are there any known symptoms of overdose or excessive use of Rhodiola Rosea?

While Rhodiola Rosea is generally well-tolerated, excessive use can lead to some adverse effects. These may include irritability, restlessness, insomnia, increased heart rate, and digestive issues. It’s important to stick to recommended dosages and consult with a healthcare professional before significantly exceeding them.

What is Rhodiola Rosea’s mode of action within the body?

Rhodiola Rosea primarily exerts its beneficial effects by acting as an adaptogen. It helps the body adapt to stress by regulating the release of stress hormones like cortisol. Additionally, it enhances the production of neurotransmitters like serotonin and dopamine, which contribute to improved mood and reduced anxiety. Rhodiola also boosts the activity of enzymes that improve the body’s energy production and resilience.

Are there any known synergistic effects when Rhodiola Rosea is combined with specific nutrients?

Yes, Rhodiola Rosea can synergize with other nutrients and herbs to enhance its effects. For example, combining it with ashwagandha may provide a more potent stress-reduction effect. Rhodiola can also work well with vitamin B complex, magnesium, and omega-3 fatty acids to support overall mental and emotional well-being. However, it’s essential to consult with a healthcare provider before combining supplements to ensure safety and proper dosages.

Does Rhodiola Rosea have a distinct aroma or essential oil that may have therapeutic benefits?

Rhodiola Rosea does have a mild, pleasant aroma, but it’s not typically used for its essential oil. The therapeutic benefits of Rhodiola are primarily attributed to its phytochemical compounds, such as salidroside and rosavin, which support its adaptogenic properties. While its aroma may have some calming effects, the main benefits come from ingestion as a supplement or herbal extract.

Are there any cultural or historical uses of Rhodiola Rosea that should be considered?

Rhodiola Rosea has a rich history of use in traditional medicine systems, particularly in Siberia and other parts of Northern Europe and Asia. It was often employed to combat fatigue, enhance endurance, and improve resilience to harsh environmental conditions. In Russia, it was used by athletes and cosmonauts to boost physical and mental performance. Understanding these historical uses can provide valuable insights into its modern applications as a natural adaptogen and stress-reducing agent.

Does Rhodiola Rosea have any spiritual or ceremonial significance in certain traditions?

Rhodiola Rosea doesn’t hold significant spiritual or ceremonial importance in traditional practices. It’s primarily valued for its medicinal properties rather than any spiritual or ritualistic significance.

Are there any variations in Rhodiola Rosea’s potency based on its geographic origin?

Yes, the potency of Rhodiola Rosea can vary based on its geographic origin. Environmental factors, such as climate, soil composition, and altitude, can influence the plant’s chemical composition. As a result, Rhodiola Rosea from different regions may have variations in its active compounds and effectiveness.

Does Rhodiola Rosea have a known effect on specific organs or body systems?

Rhodiola Rosea is known to have a broad impact on various organs and body systems. It is most notably recognized for its adaptogenic properties, which means it helps the body adapt to stress and maintain overall balance. This can positively influence the nervous system, cardiovascular system, and immune system, among others.

Are there any known interactions of Rhodiola Rosea with commonly prescribed medications?

Rhodiola Rosea may interact with certain medications. It can potentially enhance the effects of medications like anticoagulants (blood thinners), antidepressants, and diabetes medications. If you’re taking any prescription drugs, it’s crucial to consult with a healthcare professional before using Rhodiola Rosea to avoid adverse interactions.

What are the potential benefits and risks of long-term or chronic use of Rhodiola Rosea?

When considering long-term or chronic use of Rhodiola Rosea, it’s important to weigh the potential benefits and risks. Some potential benefits include improved stress resilience, enhanced mental and physical performance, and mood regulation. However, chronic use may lead to tolerance, reducing its effectiveness over time. Additionally, excessive or prolonged use could result in side effects like insomnia or digestive issues. It’s advisable to use Rhodiola Rosea in cycles or consult a healthcare provider for guidance on its extended use to minimize potential risks.

Is it advisable to cycle on and off Rhodiola Rosea to prevent tolerance or dependence?

Cycling on and off Rhodiola Rosea can be a beneficial approach to prevent tolerance or dependence. This herb is considered an adaptogen, meaning it helps your body adapt to stress. When used continuously, the body may become less responsive to its effects over time. To avoid this, some people choose to take Rhodiola Rosea for a few weeks, followed by a break of a similar duration. However, individual responses vary, so it’s essential to monitor how your body reacts and adjust your usage accordingly.

Are there any precautions regarding driving or operating machinery while using Rhodiola Rosea?

While Rhodiola Rosea is generally well-tolerated, it’s crucial to exercise caution when driving or operating machinery, especially when you’re still getting used to its effects. Some individuals may experience mild dizziness or drowsiness, although this isn’t common. To ensure your safety, it’s advisable to test your reaction to Rhodiola Rosea in a controlled environment before engaging in activities that require your full attention.

There are no specific dietary restrictions associated with Rhodiola Rosea use. However, maintaining a balanced diet and a healthy lifestyle can complement its effects. Staying hydrated, consuming nutritious meals, and getting regular exercise can enhance your overall well-being and may work synergistically with Rhodiola Rosea.

Does Rhodiola Rosea have any specific recommendations for addressing common side effects?

Common side effects of Rhodiola Rosea are typically mild and infrequent. These may include minor gastrointestinal discomfort, dry mouth, or sleep disturbances. If you experience any of these side effects, reducing the dosage or taking it with food may help alleviate them. If symptoms persist or worsen, it’s advisable to consult a healthcare professional for guidance.

Are there any known variations or subspecies of Rhodiola Rosea with different properties?

Rhodiola Rosea is primarily characterized by one primary species, Rhodiola Rosea, although there are other species within the Rhodiola genus. While they share some similarities, it’s essential to note that their properties can vary. If you are considering using a different Rhodiola species, such as Rhodiola crenulata or Rhodiola sachalinensis, it’s important to research their specific effects and consult with a healthcare provider for guidance, as their profiles may differ from the more commonly used Rhodiola rosea.

Does Rhodiola Rosea have any documented cases of misuse or abuse?

Rhodiola Rosea, a popular adaptogenic herb, has a generally safe profile with limited documented cases of misuse or abuse. It is not known for causing addiction or withdrawal symptoms when used responsibly. However, like any substance, excessive consumption can lead to adverse effects, including insomnia, jitteriness, or digestive discomfort. To avoid these issues, it’s essential to adhere to recommended dosages and consult a healthcare professional if you have concerns.

Is Rhodiola Rosea regulated or approved for medicinal use in the United States?

In the United States, Rhodiola Rosea is considered a dietary supplement, which means it is not subject to the same rigorous regulations as pharmaceutical drugs. The FDA does not approve or regulate it for specific medicinal uses. However, it is legal to purchase and use Rhodiola Rosea as a dietary supplement. To ensure safety and efficacy, look for reputable brands that adhere to good manufacturing practices (GMP) and consult with a healthcare provider before using it for specific health concerns.

Are there any known interactions of Rhodiola Rosea when combined with other medicinal herbs?

Rhodiola Rosea is generally well-tolerated, but it’s essential to be cautious when combining it with other medicinal herbs or supplements. It may interact with drugs or herbs that affect serotonin levels, such as antidepressants or St. John’s Wort, potentially leading to serotonin syndrome. Additionally, Rhodiola Rosea might enhance the effects of stimulants, so use caution when combining it with substances like caffeine. Always consult a healthcare professional before combining Rhodiola Rosea with other herbs or medications to avoid potential interactions.

How does Rhodiola Rosea’s preparation or dosage change for acute versus chronic conditions?

The preparation and dosage of Rhodiola Rosea can vary depending on whether it’s used for acute or chronic conditions. For acute situations like managing stress or fatigue, a lower dose (e.g., 100-200 mg) taken in the morning is often recommended. For chronic conditions, such as anxiety or mood disorders, a consistent daily dose (e.g., 200-600 mg) is typically suggested. The choice of standardized extract or whole root powder can also influence dosage. However, it’s crucial to consult with a healthcare provider to determine the most appropriate dosage and preparation based on your specific needs.

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Are there any known withdrawal symptoms when discontinuing the use of Rhodiola Rosea?

Rhodiola Rosea is not associated with significant withdrawal symptoms when discontinuing its use, especially when used within recommended dosages. Unlike some medications or substances, it does not create physical dependence or addiction. However, individuals who have been using Rhodiola Rosea for an extended period may experience a temporary return of symptoms related to the conditions they were addressing. To avoid potential discomfort, it’s advisable to gradually reduce the dosage when discontinuing Rhodiola Rosea under the guidance of a healthcare professional.

What are the best supplement brands of Rhodiola Rosea?

When considering supplement brands for Rhodiola Rosea, it’s important to choose reputable companies known for quality and purity. Some well-regarded brands include NOW Foods, Gaia Herbs, and Nature’s Way. However, always consult with a healthcare professional before starting any new supplement regimen to ensure it’s safe and appropriate for your specific needs.

Article References & Sources

At AncientHerbsWisdom, our content relies on reputable sources, including peer-reviewed studies, to substantiate the information presented in our articles. Our primary objective is to ensure that our content is thoroughly fact-checked, maintaining a commitment to accuracy, reliability, and trustworthiness.

  1. Rhodiola [Fact sheet]. (2016, December 1)
  2. Gao L, Wu C, Liao Y, Wang J. Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial. J Affect Disord. 2020;265:99-103. doi:10.1016/j.jad.2020.01.065
  3. Todorova V, Ivanov K, Delattre C, Nalbantova V, Karcheva-Bahchevanska D, Ivanova S. Plant adaptogens-History and future perspectives. Nutrients. 2021;13(8):2861. doi:10.3390/nu13082861
  4. Noreen, E., Buckley, J., & Lewis, S. (2009, July 31). The effects of an acute dose of Rhodiola rosea on exercise performance and cognitive function [Abstract]. Journal of the International Society of Sports Nutrition, 6(Suppl 1), 14
  5. Cropley M, Banks AP, Boyle J. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015;29(12):1934-1939. doi:10.1002/ptr.5486
  6. Lee, Y., Jung, J.-C., Jang, S., Kim, J., Ali, Z., Khan, I. A., & Oh, S. (2013). Anti-inflammatory and neuroprotective effects of constituents isolated from Rhodiola rosea. Evidence-Based Complementary and Alternative Medicine, 2013
  7. Ballmann CG, Maze SB, Wells AC, et al. Effects of short-term Rhodiola rosea (golden root extract) supplementation on anaerobic exercise performance. J Sports Sci. 2019;37(9):998-1003. doi:10.1080/02640414.2018.1538028
  8. Bystritsky, A., Kerwin, L., & Feusner, J. (2008, February 28). A pilot study of Rhodiola rosea (Rhodax®) for generalized anxiety disorder (GAD) [Abstract]. The Journal of Alternative and Complementary Medicine, 14(2), 175-180
  9. Mao JJ, Xie SX, Zee J, et al. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine. 2015;22(3):394-399. doi:10.1016/j.phymed.2015.01.010
  10. Mao, J. J., Xie, S. X., Zee, J., Soeller, I., Li, Q. S., Rockwell, K., … Amsterdam, J. D. (2015, March 15). Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine, 22(3), 394-399
  11. Kosakowska O, Bączek K, Przybył JL, et al. Antioxidant and antibacterial activity of roseroot (Rhodiola rosea L.) dry extracts. Molecules. 2018;23(7):1767. doi:10.3390/molecules23071767
  12. Hung, S. K., Perry, R., & Ernst, E. (2011, February 15). The effectiveness and efficacy of Rhodiola rosea L.: A systematic review of randomized clinical trials [Abstract]. Phytomedicine, 18(4), 235-244
  13. National Center for Complementary and Integrative Health. Rhodiola.
  14. Panossian A, Nikoyan N, Ohanyan N, et al. Comparative study of Rhodiola preparations on behavioral despair of rats. Phytomedicine. 2008;15(1-2):84-91. doi:10.1016/j.phymed.2007.10.003
  15. Pu WL, Zhang MY, Bai RY, et al. Anti-inflammatory effects of Rhodiola rosea L.: A review. Biomed Pharmacother. 2020;121:109552. doi:10.1016/j.biopha.2019.109552
  16. Young LM, Pipingas A, White DJ, Gauci S, Scholey A. A systematic review and meta-analysis of B vitamin supplementation on depressive symptoms, anxiety, and stress: Effects on healthy and ‘at-risk’ individuals. Nutrients. 2019;11(9):2232. doi:10.3390/nu11092232
  17. Ross SM. Rhodiola rosea (SHR-5), part I: A proprietary root extract of Rhodiola rosea is found to be effective in the treatment of stress-related fatigue. Holist Nurs Pract. 2014;28(2):149-154. doi:10.1097/HNP.0000000000000014
  18. Mattioli, L., & Perfumi, M. (2007, September 1). Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats [Abstract]. Journal of Psychopharmacology, 21(7), 742-750
  19. Williams TD, Langley HN, Roberson CC, et al. Effects of short-term golden root extract (Rhodiola rosea) supplementation on resistance exercise performance. Int J Environ Res Public Health. 2021;18(13):6953. doi:10.3390/ijerph18136953
  20. Boyle NB, Billington J, Lawton C, Quadt F, Dye L. A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers. Nutr Neurosci. 2022;25(9):1845-1859. doi:10.1080/1028415X.2021.1909204
  21. Ross SM. Rhodiola rosea (SHR-5), part 2: A standardized extract of Rhodiola rosea is shown to be effective in the treatment of mild to moderate depression. Holist Nurs Pract. 2014;28(3):217-221. doi:10.1097/HNP.0000000000000030
  22. Khanum F, Bawa AS, Singh B. Rhodiola rosea: A versatile adaptogen. Compr Rev Food Sci Food Saf. 2005;4(3):55-62. doi:10.1111/j.1541-4337.2005.tb00073.x
  23. Punja S, Shamseer L, Olson K, Vohra S. Rhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trial. PLoS One. 2014;9(9):e108416. doi:10.1371/journal.pone.0108416
  24. Ishaque, S., Shamseer, L., Bukutu, C., & Vohra, S. (2012, May 29). Rhodiola rosea for physical and mental fatigue: A systematic review. BMC Complementary & Alternative Medicine, 12, 70
  25. Tao H, Wu X, Cao J, et al. Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study. Med Res Rev. 2019;39(5):1779-1850. doi:10.1002/med.21564
  26. Cifani, C., Di Micioni, B. M. V., Vitale, G., Ruggieri, V., Ciccocioppo, R., & Massi, M. (2010, December 2). Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating [Abstract]. Physiology & Behavior, 101(5), 555-562
  27. Thu OK, Spigset O, Nilsen OG, Hellum B. Effect of commercial Rhodiola rosea on CYP enzyme activity in humans. Eur J Clin Pharmacol. 2016;72(3):295-300. doi:10.1007/s00228-015-1988-7
  28. Olsson, E. M. G., von Schéele, B., & Panossian, A. G. (2008, November 18). A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Medica, 75(2), 105-112
  29. Le TT, McGrath SR, Fasinu PS. Herb-drug interactions in neuropsychiatric pharmacotherapy – A review of clinically relevant findings. Curr Neuropharmacol. 2022;20(9):1736-1751. doi:10.2174/1570159X19666210809100357
  30. Khanum, F., Bawa, A. S., & Singh, B. (2005). Rhodiola rosea: A versatile adaptogen. Comprehensive Reviews in Food Science and Food Safety, 4, 55-62
  31. Thu OK, Nilsen OG, Hellum B. In vitro inhibition of cytochrome P-450 activities and quantification of constituents in a selection of commercial Rhodiola rosea products. Pharm Biol. 2016;54(12):3249-3256. doi:10.1080/13880209.2016.1223145
  32. Kelly, G. S. (2001, June). Rhodiola rosea: A possible plant adaptogen. Alternative Medicine Review, 6(3), 293-302

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